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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of proliferative vitreoretinopathy (PVR)
ncRNA name Robo1 siRNA
ncRNA Category siRNA
Disease name proliferative vitreoretinopathy (PVR)
Species Homo sapiens
Tissues/Cell_line human RPE cell line D407
Methods siRNA transfection, qRT-PCR, Western blot, MTT assay, immunofluorescence analysis, ELISA, flow cytometry
Expression pattern associated
Functional description Silencing the expression of Robo1 in RPE cells inhibited cell proliferation and suppressed the development of PVR in an animal model.
PubMed ID 20071679
Year 2010
Title Effect of Robo1 on retinal pigment epithelial cells and experimental proliferative vitreoretinopathy.
Drug-related ncRNA NO

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