ncRNA name | Robo1 siRNA |
ncRNA Category | siRNA |
Disease name | proliferative vitreoretinopathy (PVR) |
Species | Homo sapiens |
Tissues/Cell_line | human RPE cell line D407 |
Methods | siRNA transfection, qRT-PCR, Western blot, MTT assay, immunofluorescence analysis, ELISA, flow cytometry |
Expression pattern | associated |
Functional description | Silencing the expression of Robo1 in RPE cells inhibited cell proliferation and suppressed the development of PVR in an animal model. |
PubMed ID | 20071679 |
Year | 2010 |
Title | Effect of Robo1 on retinal pigment epithelial cells and experimental proliferative vitreoretinopathy. |
Drug-related ncRNA | NO |
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